Recombinant Human Ang-4 Protein
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Human Angiopoietin-4 (Ang-4) is a secreted glycoprotein belonging to the angiopoietin family. It has the characteristic structural motifs of angiopoietins including the coiled-coiled domain near the amino-terminus and a fibrinogen-like domain at the C-terminus.
SKU | OPTIONS | Price | Quantity | ||
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ANG4-100 | 50 ug (1 mg/ml) | Please inquire | |||
ANG4-200 | 1 mg (1 mg/ml) | Please inquire | |||
ANG4-300 | 100 mg (10 mg/ml) | Please inquire | |||
ANG4-400 | 1 g (10 mg/ml) | Please inquire | |||
ANG4-OEM | Any size | Please inquire |
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Description
Description
Human Angiopoietin-4 (Ang-4) is a secreted glycoprotein belonging to the angiopoietin family. It has the characteristic structural motifs of angiopoietins including the coiled-coiled domain near the amino-terminus and a fibrinogen-like domain at the C-terminus. Human Ang-4 is an agonist that can bind and activate Tie-2, a receptor tyrosine kinase with immunoglobulin and epidermal growth factor homology domains expressed primarily on endothelial cells and early hematopoietic cells.
Full Name
Angiopoietin-4
Source
E. coli
Species
Human
Accession #
Q9Y264
Molecule Weight
The mature recombinant human Ang-4 is a 57 kDa protein containing 480aa (N24-I503).
Purity
> 95 % as determined by SDS-PAGE
Endotoxin
< 0.1 EU per μg of the protein as determined by the LAL method
Activity
Measured by its ability to compete with biotinylated rhAng-2 for binding to immobilized Tie-2/Fc Chimera in a functional ELISA. Compared to rmAngiopoietin-3, rhAngiopoietin-4 is less effective in this competitive assay.
Storage
-80 Avoid repeated freeze-thaw cycles.
Storage Buffer
PBS
Additional information
OPTIONS | 50 ug (1 mg/ml), 1 mg (1 mg/ml), 100 mg (10 mg/ml), 1 g (10 mg/ml), Any size |
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