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Recombinant Human INF-alpha 16 Protein
Recombinant Human INF-alpha 16 Protein

The interferons (IFN)s are a family of cytokines with potent antiviral, antitumor, and immunomodulatory properties.
 
Name Cat# Description Price Qty
Human INF-alpha 16 Protein
INFA16-100
50 ug (1 mg/ml)
please inquire
Human INF-alpha 16 Protein
INFA16-200
1 mg (1 mg/ml)
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Human INF-alpha 16 Protein
INFA16-300
100 mg (10 mg/ml)
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Human INF-alpha 16 Protein
INFA16-400
1 g (10 mg/ml)
please inquire
Human INF-alpha 16 Protein
INFA16-OEM
Any size
please inquire

Description
The interferons (IFN)s are a family of cytokines with potent antiviral, antitumor, and immunomodulatory properties. Interferons are increasingly used clinically to treat a range of malignancies, myelodysplasias and autoimmune diseases. Interferons are divided into type I, II, and III. Type I IFNs (IFN-α and IFN-β) are most abundant in number, distribution, and expression.
IFN-α16 (interferon α 16) belongs to type 1 interferon family.  IFN-α16 is induced in peripheral blood mononuclear cells (PBMCs) upon incubation with CpG-oligonucleotides and in plasmacytoid dendritic cells upon incubation with CpG-oligonucleotides or imiquimod. Human IFN-α16 is classified as an intermediate ISG inducer with a moderate capacity to induce IFIT1, CXCL10, CXCL11, ISG15 and CCL8.
Human IFN-α16 expression is IFN-α receptor-dependent (i.e. induced by other IFN-α subtypes) only under conditions of low viral multiplicity of infection (MOI) of Sendai virus in vitro.

Full Name
Interferon α 16


Source
E. coli


Species
Human


Accession #
P05015


 Molecule Weight
The mature recombinant human IFN-α16 is a 22 kDa protein (24-189aa).


Purity
> 95 % as determined by SDS-PAGE


Endotoxin
< 0.1 EU per μg of the protein as determined by the LAL method


Storage
-80     Avoid repeated freeze-thaw cycles.

Storage Buffer
PBS

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