Description:
T4 replication helicase (gp41) and polymerase (gp43) can be assembled onto a loading site located near the end of a long double-stranded DNA template in the presence of a macro-molecular crowding agent, and that this coupled “two-protein” system can carry out ATP-dependent strand displacement DNA synthesis at physiological rates (400 to 500 bp per sec) and with high processivity in the absence of other T4 DNA replication proteins.
DNA helicase is an enzyme that aids in DNA synthesis by 'unzipping' the two strands of a DNA helix so that DNA polymerase can access the DNA to add nucleotides and effect copying.
Source:
An enzyme from the gene of the bacteriophage T4 phage.
Applications:
This product has not been tested for any functionality. Full length proteins may or may not have enzymatic activity. Any customer feedback on functionality would be greatly appreciated.
Recommended Storage Conditions:
-20°C
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