Description:
MCLAB’s 7M Guanidine-HCl Solution is a ready-to-use solution of guanidine hydrochloride, that can be easily diluted and pH-adjusted to any concentration below 7M. In addition to increasing solubility of hydrophobic molecules, guanidine is a general protein denaturant, unfolding proteins and altering their structures. This can cause some proteins to be irreversibly altered upon interaction with guanidine solutions and may lose their binding function. Before any significant use of guanidine, it is best to experiment with a small amount of the sample and conclude whether the denaturing effects will adversely affect the intended use of the protein.

Applications:

• Solubilizing proteins from inclusion bodies
• Increasing solubility of hydrophobic peptides and proteins
• Denaturing proteins

Recommended Storage Condition:
Store at room temperature

Caution: EXTREMELY CORROSIVE, HANDLE WITH CARE! Avoid ingestion and contact with skin.