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Human Brain-Derived Neurotrophic Factor (BDNF) is a member of the Nerve growth factor family. BDNF is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. During development, BDNF promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems.
Human Neurotrophin-3 (NT-3) is a member of the neurotrophin family.
Human Neurotrophin-4 (NT-4), also known as NT-5, is a neurotrophic factor structurally related to β-NGF, BDNF, and NT-3.
Nerve growth factor (NGF) is important for the development and maintenance of the sympathetic and sensory nervous systems.
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Nerve Growth Factor (NGF) holds great therapeutic promise for Alzheimer’s disease, diabetic neuropathies, ophthalmic diseases, and dermatological ulcers.
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