Nucleases

Nucleases

  •  per page
Benzonase Endonuclease
Benzonase endonuclease from Serratia marcescens, can be used to degrade all forms of DNA and RNA while having no proteolytic activity.
Click To Get More Details >>
Cas12a Nuclease
CRISPR-Cas systems are powerful tools for mediating nucleic acids. Cas12a (also referred as Cpf1) nuclease belonging to the Class 2, Type V CRISPR system.
Click To Get More Details >>
Cas13a (CRISPR Associated Protein 13a)
Adaptive immune systems from prokaryotes utilize clustered regularly interspaced short palindromic
repeats (CRISPRs) and CRISPR associated (Cas) proteins to cleave foreign genetic material. Cas13a, (previously referred to as C2c2) is part of the Type VI CRISPR-Cas system.
Click To Get More Details >>
Cas13d
Adaptive immune systems from prokaryotes utilize clustered regularly interspaced short palindromic
repeats (CRISPRs) and CRISPR associated (Cas) proteins to cleave foreign genetic material. Cas13a, (previously referred to as C2c2) is part of the Type VI CRISPR-Cas system.
Click To Get More Details >>
Cas9 Nuclease

Cas9 Nuclease, Streptococcus pyogenes, is an RNA-guided endonuclease that catalyzes site-specific cleavage of double stranded DNA.

Click To Get More Details >>
dCas13a
Adaptive immune systems from prokaryotes utilize clustered regularly interspaced short palindromic
repeats (CRISPRs) and CRISPR associated (Cas) proteins to cleave foreign genetic material. Cas13a, (previously referred to as C2c2) is part of the Type VI CRISPR-Cas system.
Click To Get More Details >>
dCas13d
Adaptive immune systems from prokaryotes utilize clustered regularly interspaced short palindromic
repeats (CRISPRs) and CRISPR associated (Cas) proteins to cleave foreign genetic material. Cas13a, (previously referred to as C2c2) is part of the Type VI CRISPR-Cas system.
Click To Get More Details >>
Exonuclease VII

Exonuclease VII, (Exo VII) derived from E. coli, cleaves single-stranded DNA (ssDNA) from both 5´→3´ and 3´→5´ directions.

Click To Get More Details >>
T4 Endonuclease VII
Endonuclease VII is the product of gene 49 of bacteriophage T4. It has a mass of 18 kDa. T4 Endonuclease VII involves in DNA-packaging, genetic recombination and mismatch repair in vivo.
Click To Get More Details >>
T7 Exonuclease
T7 Exonuclease is similar to Lambda Exonuclease in that it catalyzes the stepwise hydrolysis of duplex DNA from the 5' termini liberating 5' mononucleotides. However, unlike Lambda Exonuclease, the enzyme has low processivity and it removes both 5’-hydroxyl and 5’-phosphoryl termini.
Click To Get More Details >>
Lambda Exonuclease
Lambda Exonuclease catalyzes the hydrolysis of inorganic pyrophosphate to form orthophosphate.
Click To Get More Details >>
FEN1 (AFU)
FEN1 (AFU) is a recombinant flap endonuclease-1 (FEN-1) protein from the E. coli containing FEN1 gene of hyperthermophilic Archaea strain, Archaeoglobus fulgidus. The FEN1 removes 5' overhanging flaps in DNA repair and processes the 5' ends of Okazaki fragments in lagging strand DNA synthesis.
Click To Get More Details >>
Exonuclease III (<i>E. coli</i>)
Exonuclease III is a 3′→ 5′ exonuclease which acts by digesting one strand of a dsDNA duplex at a time or digesting the RNA strand of an RNA-DNA heteroduplex (1).
Click To Get More Details >>
Exonuclease I (<i>E. coli</i>)
Exonuclease I cleaves single-stranded DNA in the 3′→ 5′ direction, releasing 5′ -mono/di-nucleotides and leaving double-stranded DNA molecules and the 5'-terminus intact.
Click To Get More Details >>
  •  per page