Nucleocapsid Protein (N-protein)
Nucleocapsid Protein (N-protein)

Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry.
 
Name Cat# Description Price Qty
N-protein (No His tag)
NP-100
1 mg, 1 mg/ml
$412.50
N-protein (No His tag)
NP-200
1 g, 1 mg/ml
please inquire
N-protein (N-terminal His tag)
NPHN-100
1 mg, 1 mg/ml
$412.50
N-protein (N-terminal His tag)
NPHN-200
1 g, 1 mg/ml
please inquire
N-protein (C-terminal His tag)
NPHC-100
1 mg, 1 mg/ml
$412.50
N-protein (C-terminal His tag)
NPHC-200
1 g, 1 mg/ml
please inquire
N-protein Biotinylated
NPBIO-100
50 μg,1 mg/ml
please inquire
N-protein Biotinylated
NPBIO-200
1 mg,1 mg/ml
please inquire
N-protein Magnetic beads
NPMAG-100
50 μg
please inquire
N-protein Magnetic beads
NPMAG-200
1 mg
please inquire
N-protein Agarose beads affinity resin
NPAGA-100
50 μg
please inquire
N-protein Agarose beads affinity resin
NPAGA-200
1 mg
please inquire
N-protein Polystyrene beads (100nm) coated
NPPOL-100
please inquire
N-protein Gold nano-particle
NPGOLD-100
please inquire
N-protein HRP conjugated
NPHRP-100
50 μg,1 mg/ml
please inquire
N-protein HRP conjugated
NPHRP-200
1 mg,1 mg/ml
please inquire

Description
Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleocapsid protein (N-protein) is a structural protein that binds to the coronavirus RNA genome, thus creating a shell (or capsid) around the enclosed nucleic acid. The N-protein also interacts with the viral membrane protein during viral assembly, assists in RNA synthesis and folding, plays a role in virus budding, and affects host cell responses, including cell cycle and translation. The N-protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. The N-protein is a most abundant protein of coronavirus. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool. The array of diverse functional activities accommodated in the N protein goes far beyond to be a static structural protein and makes it an interesting target in the development of antiviral therapeutics.

Source
E. coli

Organism
COVID-19

Accession #
QHO62115.1

Molecule Weight
The recombinant COVID-19 Nucleocapsid Protein consists of 420 amino acids (Met 1-Ala 419) and predicts a molecular mass of 47 kDa.

Endotoxin
< 1.0 EU per μg protein as determined by the LAL method

Purity
> 95 % as determined by SDS-PAGE

Storage
-80 Avoid repeated freeze-thaw cycles.

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