Recombinant Human Ang-4 Protein
Recombinant Human Ang-4 Protein

Human Angiopoietin-4 (Ang-4) is a secreted glycoprotein belonging to the angiopoietin family. It has the characteristic structural motifs of angiopoietins including the coiled-coiled domain near the amino-terminus and a fibrinogen-like domain at the C-terminus.
 
Name Cat# Description Price Qty
Human Ang-4 Protein
ANG4-100
50 ug (1 mg/ml)
please inquire
Human Ang-4 Protein
ANG4-200
1 mg (1 mg/ml)
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Human Ang-4 Protein
ANG4-300
100 mg (10 mg/ml)
please inquire
Human Ang-4 Protein
ANG4-400
1 g (10 mg/ml)
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Human Ang-4 Protein
ANG4-OEM
Any size
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Description
Human Angiopoietin-4 (Ang-4) is a secreted glycoprotein belonging to the angiopoietin family. It has the characteristic structural motifs of angiopoietins including the coiled-coiled domain near the amino-terminus and a fibrinogen-like domain at the C-terminus.  Human Ang-4 is an agonist that can bind and activate Tie-2, a receptor tyrosine kinase with immunoglobulin and epidermal growth factor homology domains expressed primarily on endothelial cells and early hematopoietic cells.

Full Name
Angiopoietin-4

Source
E. coli

Species
Human

Accession #
Q9Y264

Molecule Weight
The mature recombinant human Ang-4 is a 57 kDa protein containing 480aa (N24-I503).

Purity
> 95 % as determined by SDS-PAGE

Endotoxin
< 0.1 EU per μg of the protein as determined by the LAL method

Activity
Measured by its ability to compete with biotinylated rhAng-2 for binding to immobilized Tie-2/Fc Chimera in a functional ELISA. Compared to rmAngiopoietin-3, rhAngiopoietin-4 is less effective in this competitive assay.

Storage
-80     Avoid repeated freeze-thaw cycles.

Storage Buffer
PBS

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