Recombinant Human BMP-5 Protein
Recombinant Human BMP-5 Protein

BMP-5 is a member of the Bone Morphogenetic Protein (BMPs) family, which is important for the development of bone and cartilage.
 
Name Cat# Description Price Qty
Human BMP-5 Protein
BMP5-100
50 ug (1 mg/ml)
please inquire
Human BMP-5 Protein
BMP5 -200
1 mg (1 mg/ml)
please inquire
Human BMP-5 Protein
BMP5 -300
100 mg (10 mg/ml)
please inquire
Human BMP-5 Protein
BMP5 -400
1 g (10 mg/ml)
please inquire
Human BMP-5 Protein
BMP5 -OEM
Any size
please inquire

Description
BMP-5 is a member of the Bone Morphogenetic Protein (BMPs) family, which is important for the development of bone and cartilage. BMPs belong to the TGF-β superfamily of structurally related signaling proteins. BMP proteins are synthesized as large precursor molecules that are cleaved by proteolytic enzymes. The active form of BMPs can consist of a dimer of two identical proteins or a heterodimer of two related bone morphogenetic proteins. BMPs signal through type I and type II receptor tyrosine kinases and signal through SMAD proteins.
BMP-5 is expressed in the nervous system, lungs and liver. It is a known regulator for dendritic growth in sympathetic neurons. 

Full Name
Bone morphogenetic protein 5

Source
E. coli

Species
Human

Accession #
P22003

Molecule Weight
The mature recombinant human BMP-5 consists of 148 amino acids (317-454) and has a predicted molecular mass of 19 kDa.

Purity
> 95 % as determined by SDS-PAGE

Endotoxin
< 0.1 EU per μg of the protein as determined by the LAL method

Activity
Measured by its ability to induce alkaline phosphatase production by ATDC5 mouse chondrogenic cells. The ED50 for this effect is 0.5-2 µg/mL.

Storage
-80     Avoid repeated freeze-thaw cycles.

Storage Buffer
PBS

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