Recombinant Human Betacellulin (BTC) Protein
Recombinant Human Betacellulin (BTC) Protein

Betacellulin is an EGF-related polypeptide growth factor that signals through the EGF receptor.
 
Name Cat# Description Price Qty
Human BTC Protein
BTC-100
50 ug (1 mg/ml)
please inquire
Human BTC Protein
BTC-200
1 mg (1 mg/ml)
please inquire
Human BTC Protein
BTC-300
100 mg (10 mg/ml)
please inquire
Human BTC Protein
BTC-400
1 g (10 mg/ml)
please inquire
Human BTC Protein
BTC-OEM
Any size
please inquire

Description
Betacellulin is an EGF-related polypeptide growth factor that signals through the EGF receptor. It is produced in several tissues, including the pancreas, small intestine, and in certain tumor cells. Betacellulin is a potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells. Human Betacellulin is initially synthesized as a glycosylated 32.0 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce the mature sequence. 

Full Name
Betacellulin

Source
E. coli

Species
Human

Accession #
P35070

Molecule Weight
The mature recombinant human BTC is a 9 kDa protein containing 80aa (D32-Y111).

Purity
> 95 % as determined by SDS-PAGE

Endotoxin
< 0.1 EU per μg of the protein as determined by the LAL method

Activity
The ED50 was determined by the dose-dependent stimulation of the proliferation of murine Balb/3T3 cells is ≤ 0.05 ng/ml, corresponding to a specific activity of ≥ 2 x 107units/mg.

Storage
-80     Avoid repeated freeze-thaw cycles.

Storage Buffer
PBS

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