Description
FGF-16 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. 
FGF16 signals through FGFR 2c and 3c. FGF-16 plays a role in the development of the central nervous system.

Full Name
Fibroblast Growth Factor 16

Source
E. coli

Species
Human

Accession #
O43320

Molecule Weight
The mature recombinant human FGF-16 consists of 206 amino acids (2-207) and has a predicted molecular mass of 23.7 kDa.

Purity
> 95 % as determined by SDS-PAGE

Endotoxin
< 0.1 EU per μg of the protein as determined by the LAL method

Activity
Measured in a cell proliferation assay using NR6R‑3T3 mouse fibroblast cells. The ED50 for this effect is 7.5-30 ng/mL.

Storage
-80     Avoid repeated freeze-thaw cycles.

Storage Buffer
PBS