Recombinant Human IGF-1 Protein
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Insulin-like growth factor I, also known as somatomedin C, is the dominant effector of growth hormone IGF-I/IGF-1 induces the proliferation, migration, and differentiation of a wide variety of cell types during development and postnatally.
SKU | OPTIONS | Price | Quantity | ||
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IGF1-100 | 50 ug (1 mg/ml) | Please inquire | |||
IGF1-200 | 1 mg (1 mg/ml) | Please inquire | |||
IGF1-300 | 100 mg (10 mg/ml) | Please inquire | |||
IGF1-400 | 1 g (10 mg/ml) | Please inquire | |||
IGF1-OEM | Any size | Please inquire |
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Description
Description
Insulin-like growth factor I, also known as somatomedin C, is the dominant effector of growth hormone IGF-I/IGF-1 induces the proliferation, migration, and differentiation of a wide variety of cell types during development and postnatally. IGF-I/IGF-1 regulates glucose and fatty acid metabolism, steroid hormone activity, and cartilage and bone metabolism. It plays an important role in muscle regeneration and tumor progression. IGF-I/IGF-1 binds IGF-I R, IGF-II R, and the insulin receptor, although its effects are mediated primarily by IGF-I R. IGF-I/IGF-1 association with IGF binding proteins increases its plasma half‑life and modulates its interactions with receptors.
Full Name
Insulin-like Growth Factor 1
Source
E. coli
Species
Human
Accession #
P05019
Molecule Weight
The mature recombinant human IGF-1 is a 7.6 kDa protein containing 70aa (G49-A118).
Purity
> 95 % as determined by SDS-PAGE
Endotoxin
< 0.1 EU per μg of the protein as determined by the LAL method
Activity
Measured in a serum-free cell proliferation assay using MCF‑7 human breast cancer cells. The ED50 for this effect is 0.3-1.5 ng/mL.
Storage
-80 Avoid repeated freeze-thaw cycles.
Storage Buffer
PBS
Additional information
OPTIONS | 50 ug (1 mg/ml), 1 mg (1 mg/ml), 100 mg (10 mg/ml), 1 g (10 mg/ml), Any size |
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