Recombinant Human INF-alpha 1 Protein
Recombinant Human INF-alpha 1 Protein

The interferons (IFN)s are a family of cytokines with potent antiviral, antitumor, and immunomodulatory properties.
 
Name Cat# Description Price Qty
Human INF-alpha 1 Protein
INFA1-100
50 ug (1 mg/ml)
please inquire
Human INF-alpha 1 Protein
INFA1-200
1 mg (1 mg/ml)
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Human INF-alpha 1 Protein
INFA1-300
100 mg (10 mg/ml)
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Human INF-alpha 1 Protein
INFA1-400
1 g (10 mg/ml)
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Human INF-alpha 1 Protein
INFA1-OEM
Any size
please inquire

Description
The interferons (IFN)s are a family of cytokines with potent antiviral, antitumor, and immunomodulatory properties. Interferons are increasingly used clinically to treat a range of malignancies, myelodysplasias and autoimmune diseases. Interferons are divided into type I, II, and III. Type I IFNs (IFN-α and IFN-β) are most abundant in number, distribution, and expression.
IFN-α1 (interferon α 1) belongs to type 1 interferon family, and is a lymphoid factor. IFN-α1 interacts with IFNAR1 (interferon α receptor 1) and IFNAR2. The interaction activates JAK1 (janus-activated kinase 1) and tyrosine kinase 2. These events phosphorylate and activate STAT1 and STAT2 (signal transducer and activator of transcription proteins), leading to the upregulation of interferon-stimulated genes some of which encode antiviral proteins.

Full Name
Interferon α 1

Source
E. coli

Species
Human

Accession #
J00210

Molecule Weight
The mature recombinant human IFN-α1 is a 19.3kDa protein containing 166 amino acid residues.

Purity
> 95 % as determined by SDS-PAGE

Endotoxin
< 0.1 EU per μg of the protein as determined by the LAL method

Storage
-80     Avoid repeated freeze-thaw cycles.

Storage Buffer
PBS

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