Recombinant Human Neurturin Protein
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Neurturin is a disulfide-linked homodimer neurotrophic factor structurally related to GDNF, artemin, and persephin.
SKU | OPTIONS | Price | Quantity | ||
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NRTN-100 | 50 ug,1 mg/ml | Please inquire | |||
NRTN -200 | 1 mg,1 mg/ml | Please inquire | |||
NRTN -300 | 100 mg,10 mg/ml | Please inquire | |||
NRTN -400 | 1 g,10 mg/ml | Please inquire | |||
NRTN -OEM | Any size | Please inquire |
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Description
Description
Neurturin is a disulfide-linked homodimer neurotrophic factor structurally related to GDNF, artemin, and persephin. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. Neurturin signals through a multicomponent receptor system, composed of RET and one of four GFRα (α1-α4) receptors. Neurturin promotes the development and survival of sympathetic and sensory neurons by signaling through a receptor system composed of RET and GFRα2.
The functional form of human neurturin is a disulfide-linked homodimer, of two 11.8 kDa polypeptide monomers (204 total amino acid residues.
Full Name
Human Neurturin protein
Source
E. coli
Species
Human
Accession #
Q99748
Molecule Weight
The mature recombinant human Neurturin protein consists of 102 amino acids (96-197) and has a predicted molecular mass of 23.6 kDa as a dimer.
Purity
> 95 % as determined by SDS-PAGE
Endotoxin
< 0.1 EU per μg of the protein as determined by the LAL method
Activity
Measured in a cell proliferation assay using SH‑SY5Y human neuroblastoma cells. The ED50 for this effect is typically 20-80 ng/mL.
Storage
-80 Avoid repeated freeze-thaw cycles.
Storage Buffer
PBS
Additional information
OPTIONS | 50 ug,1 mg/ml, 1 mg,1 mg/ml, 100 mg,10 mg/ml, 1 g,10 mg/ml, Any size |
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