Recombinant Human PIGF Protein
Recombinant Human PIGF Protein

Placenta growth factor (PlGF) is a member of the PDGF/VEGF family of growth factors. PlGF induces monocyte activation, migration, and production of inflammatory cytokines and VEGF.
 
Name Cat# Description Price Qty
Human PIGF Protein
PIGF-100
50 ug (1 mg/ml)
please inquire
Human PIGF Protein
PIGF-200
1 mg (1 mg/ml)
please inquire
Human PIGF Protein
PIGF-300
100 mg (10 mg/ml)
please inquire
Human PIGF Protein
PIGF-400
1 g (10 mg/ml)
please inquire
Human PIGF Protein
PIGF-OEM
Any size
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Description
Placenta growth factor (PlGF) is a member of the PDGF/VEGF family of growth factors. PlGF induces monocyte activation, migration, and production of inflammatory cytokines and VEGF. These activities facilitate wound, bone fracture, and cardiac repair, but also contribute to inflammation in active sickle cell disease and atherosclerosis. PlGF can also inhibit TIMP3 expression in the spleen, leading to immune triggering of hypertension.
Alternative splicing results in at least three human mature PlGF forms containing 131 (PlGF-1), 152 (PlGF-2), and 203 (PlGF-3) amino acids (aa) respectively. 

Full Name
Placenta growth factor

Source
E. coli

Species
Human

Accession #
P49763-2

Molecule Weight
The mature recombinant human PlGF is a 15 kDa protein (21-149aa).

Purity
> 95 % as determined by SDS-PAGE

Endotoxin
< 0.1 EU per μg of the protein as determined by the LAL method

Activity
When Recombinant Human VEGF R1/Flt‑1 Fc Chimera is immobilized at 0.5 μg/mL, 100 μL/well, the concentration of Recombinant Human PlGF that produces 50% of the optimal binding response is approximately 0.15-0.9 ng/mL.

Storage
-80     Avoid repeated freeze-thaw cycles.

Storage Buffer
PBS

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