Description
Vascular endothelial growth factor B VEGF-B), also known as vascular permeability factor (VPF), is a potent polypeptide regulator of blood vessel function. VEGF promotes an array of responses in the endothelium, including hyperpermeability, endothelial cell growth, angiogenesis, and enhanced glucose transport. It is a member of the PDGF family that is characterized by the presence of eight conserved cysteine residues and a cystine knot structure.

Full Name
Vascular endothelial growth factor B

Source
E. coli

Species
Human

Accession #
AAA91463

Molecule Weight
The mature recombinant human VEGF-B is a 19 kDa protein (22-188aa).

Purity
> 95 % as determined by SDS-PAGE

Endotoxin
< 0.1 EU per μg of the protein as determined by the LAL method

Activity
Measured by its binding ability in a functional ELISA. Immobilized recombinant rat Neuropilin-1 Fc Chimera at 4 µg/mL (100 µL/well) can bind recombinant human VEGF-B with a linear range of 0.3-20 ng/mL.
 
Storage
-80     Avoid repeated freeze-thaw cycles.

Storage Buffer
PBS