Description
The Wnts is a large family of secreted proteins with roles in pattern formation, cell fate decision, axon guidance, and tumor formation. Wnt signaling induces and maintains the transformed phenotype and, in certain embryonic cell lines, supports self-renewal in the absence of significant differentiation. Elevated levels of Wnt proteins are associated with tumorigenesis and are present in numerous human breast cancers. Wnt family members are highly hydrophobic, and possess 22 to 24 conserved cysteines.
Wnt-10a is a presumably secreted, glycosylated member of the Wnt family of developmental proteins.  Wnt-10a is produced by tumors and thymic epithelium.

Full Name
Wingless-type MMTV Integration Site Family Member 10a

 Source
E. coli

Species
Human

Accession #
Q9GZT5

Molecule Weight
The mature recombinant human Wnt-10a is a 44 kDa protein containing 382aa (Q36-K417).

Purity
> 95 % as determined by SDS-PAGE

Endotoxin
< 0.1 EU per μg of the protein as determined by the LAL method

Storage
-80     Avoid repeated freeze-thaw cycles.

Storage Buffer
PBS