Recombinant Human Wnt-3a Protein

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The Wnts is a large family of secreted proteins with roles in pattern formation, cell fate decision, axon guidance, and tumor formation.

SKU: SKU49572 Categories: ,
SKU OPTIONS PriceQuantity
WNT3a-100 50 ug (1 mg/ml) Please inquire
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WNT3a -200 1 mg (1 mg/ml) Please inquire
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WNT3a -300 100 mg (10 mg/ml) Please inquire
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WNT3a -400 1 g (10 mg/ml) Please inquire
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WNT3a -OEM Any size Please inquire
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Description

Description
The Wnts is a large family of secreted proteins with roles in pattern formation, cell fate decision, axon guidance, and tumor formation. Wnt signaling induces and maintains the transformed phenotype and, in certain embryonic cell lines, supports self-renewal in the absence of significant differentiation. Elevated levels of Wnt proteins are associated with tumorigenesis and are present in numerous human breast cancers. Wnt family members are highly hydrophobic, and possess 22 to 24 conserved cysteines.
Wnt-3a is necessary for proper development of the hippocampus, anterior-posterior patterning, somite development, and tailbud formation. Wnt-3a also promotes self-renewal of hematopoietic stem cells, neural stem cells, and embryonic stem cells sites.

 Full Name
Wingless-type MMTV Integration Site Family Member 3a

 Source
E. coli

Species
Human

Accession #
NP_149122

Molecule Weight
The mature recombinant human Wnt-3a is a 37.4 kDa protein containing 334aa (Ser19-Lys352).

Purity
> 95 % as determined by SDS-PAGE

Endotoxin
< 0.1 EU per μg of the protein as determined by the LAL method

Storage
-80     Avoid repeated freeze-thaw cycles.

Storage Buffer
PBS

Additional information

OPTIONS

50 ug (1 mg/ml), 1 mg (1 mg/ml), 100 mg (10 mg/ml), 1 g (10 mg/ml), Any size

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