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Artemin protein is a member of the glial cell line-derived neurotrophic factor (GDNF) family of ligands which are a group of ligands within the TGF-beta superfamily of signaling molecules. GDNFs are unique in having neurotrophic properties and have potential use for gene therapy in neurodegenerative disease.
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BMP-10 is a member of the Bone Morphogenetic Protein (BMPs) family, which is important for the development of bone and cartilage.
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BMP-15, also known as GDF-9b, is a member of the Bone Morphogenetic Protein (BMPs) family, which is important for the development of bone and cartilage.
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BMP-2 is a member of the Bone Morphogenetic Protein (BMPs) family, which is important for the development of bone and cartilage.
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BMP-3 is a member of the Bone Morphogenetic Protein (BMPs) family, which is important for the development of bone and cartilage.
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BMP-4 is a member of the Bone Morphogenetic Protein (BMPs) family, which is important for the development of bone and cartilage.
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BMP-5 is a member of the Bone Morphogenetic Protein (BMPs) family, which is important for the development of bone and cartilage.
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BMP-6 is a member of the Bone Morphogenetic Protein (BMPs) family, which is important for the development of bone and cartilage.
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BMP-7 is a member of the Bone Morphogenetic Protein (BMPs) family, which is important for the development of bone and cartilage.
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BMP-8, also known as osteogenic protein 2 (OP2), is a member of the Bone Morphogenetic Protein (BMPs) family, which is important for the development of bone and cartilage.
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BMP-8, also known as osteogenic protein 2 (OP2), is a member of the Bone Morphogenetic Protein (BMPs) family, which is important for the development of bone and cartilage.
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BMP-9, also known as growth and differentiation factor 2 (GDF-2), is a member of the Bone Morphogenetic Protein (BMPs) family, which is important for the development of bone and cartilage. BMPs belong to the TGF-β superfamily of structurally related signaling proteins.
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Glial Cell Line-Derived Neurotrophic Factor (GDNF) is a disulfide-linked homodimeric glycoprotein that belongs to the TGF-β superfamily. It has been shown to promote the survival of various neuronal subpopulations in both the central as well as the peripheral nervous systems at different stages of their development.
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Neurturin is a disulfide-linked homodimer neurotrophic factor structurally related to GDNF, artemin, and persephin.
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Persephin belongs to the GDNF ligand subfamily of the TGF-beta superfamily.
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TGF-beta 1 (transforming growth factor beta 1) is one of three closely related mammalian members, TGF-beta 1, -2 and -3 , of the large TGF-beta superfamily that share a characteristic cystine knot structure. These three TGF-beta isoforms are highly pleiotropic cytokines that are proposed to act as cellular switches that regulate processes such as immune function, proliferation and epithelial-mesenchymal transition.
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TGF-beta 2 (transforming growth factor beta 1) is one of three closely related mammalian members, TGF-beta 1, -2 and -3 , of the large TGF-beta superfamily that share a characteristic cystine knot structure. These three TGF-beta isoforms are highly pleiotropic cytokines that are proposed to act as cellular switches that regulate processes such as immune function, proliferation and epithelial-mesenchymal transition.
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TGF-beta 3 (transforming growth factor beta 1) is one of three closely related mammalian members, TGF-beta 1, -2 and -3 , of the large TGF-beta superfamily that share a characteristic cystine knot structure. These three TGF-beta isoforms are highly pleiotropic cytokines that are proposed to act as cellular switches that regulate processes such as immune function, proliferation and epithelial-mesenchymal transition.
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TGF-beta 5 is a member of the TGF-beta family of growth factors. These proteins are stable, multifunctional factors with a wide variety of effects on the growth and differentiation of virtually all cell types.
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