Adaptive immune systems from prokaryotes utilize clustered regularly interspaced short palindromic
repeats (CRISPRs) and CRISPR associated (Cas) proteins to cleave foreign genetic material. Cas13a, (previously referred to as C2c2) is part of the Type VI CRISPR-Cas system.
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repeats (CRISPRs) and CRISPR associated (Cas) proteins to cleave foreign genetic material. Cas13a, (previously referred to as C2c2) is part of the Type VI CRISPR-Cas system.
Adaptive immune systems from prokaryotes utilize clustered regularly interspaced short palindromic
repeats (CRISPRs) and CRISPR-associated (Cas) proteins to cleave foreign genetic material. Cas13d is part of the Type VI CRISPR-Cas system.
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repeats (CRISPRs) and CRISPR-associated (Cas) proteins to cleave foreign genetic material. Cas13d is part of the Type VI CRISPR-Cas system.
High quality deoxynucleotide triphosphate (dNTPs) are functionally tested in long PCR to be PCR qualified, and meet or exceed the criteria for high-quality sequencing with Thermo Sequenase DNA polymerase.
DEPC-treated Water is deionized, high quality, molecular biology grade water.
The dGTP BrightDye® Terminator Cycle Sequencing Kit is optimized for sequencing GC-rich and other difficult-to-sequence templates.
The DH10B competent E. coli has a transformation efficiency of 1 x 109 cfu/µg for supercoiled DNA and is ideal for high-efficiency cloning and plasmid propagation. It allows stable replication of high-copy number plasmids. In comparison with DH5a, methylated DNA from genomic preparation could be efficiently transformed into DH10B, therefor, the DH10B cells are more applicable than DH5a in generating genomic libraries containing methylated cytosine or adenine residues.
DH5a™ is the most frequently used E. coli strain for routine cloning applications.
Direct DNA Solution is for purifying genomic DNA from a variety of sample types, such as whole blood, tissues, bone marrow, buffy coat, body fluids, cultured cells, cell suspensions, and Gram-negative bacteria.
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Direct RNA Solution is a RT-PCR ready RNA extraction solution. It can extract RNA from a variety of sample types, such as whole blood, tissues, body fluids, cultured cells, plant leaves, roots, flowers, fungi, and bacteria.
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mRNA sequencing (mRNA-Seq) delivers unbiased and unparalleled information about the transcriptome without probe design. Strand information provides increased confidence in transcript annotation, particularly for non-human samples, and may increase the percentage of alignable reads, reducing sequencing costs per sample. Strand orientation also enables the detection of antisense expression, providing visibility to regulatory relationships that would otherwise be missed.
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The MCLAB DNA dA-Tailing Kit is used to add an “A” base to the 3´ end of a blunt phosphorylated DNA fragment. This treatment creates compatible overhangs for the next step of DNA sample preparation.
MCLAB's DNA fragment analysis services help customers to determine the size and the amount of the fluorescent labeled DNA fragments in samples. The labeled DNA fragments are separated on ABIs Genetic Analyzers (3730XL).
MCLab’s DNA Fragment Size Analysis Kit offers fast and reliable separation, sizing and quantification of DNA or RNA libraries utilizing Capillary Electrophoresis technology, which can separate molecules with a single base difference.
DNA Homopolymeric Tailing Super Mix provides qualified reagents for the addition of homopolymer tails to the 3' ends of DNA with terminal deoxynucleotidyl transferase (TdT).
The MCLAB's DNA Ligation Kit is used to ligate DNA adapters to dA-tailed DNA fragments. The kit has been optimized to the maximum efficiency and convenience in DNA sample preparation workflow.
MCLAB offers a variety of quality, fast and low cost mutagenesis services.
DNA Polymerase I is a DNA-dependent DNA polymerase. The enzyme catalyzes 5' -> 3' synthesis of DNA and exhibits 3' -> 5’ exonuclease proofreading activity.
DNA polymerase from Thermotoga neapolitana was identified[1] as an enzyme that is able to withstand the protein-denaturing conditions (high temperature) required during PCR[2].
MCLAB's DNA Size Standard series products are internal lane standards that are intended to be used in assigning sizes to DNA fragments on fluorescence-detecting instruments. The common applications include genotyping and DNA fragment Analysis.
Low concentration solutions of DNA are prone to DNA degradation or other loss. It is critical that optimal methods are employed for DNA suspension and long-term storage.
